First, what is Androgenetic alopecia?
Androgenetic alopecia, also known as pattern balding, is the most prevalent form of hair loss for men and women. “Andro” is the Greek prefix for “male,” “man,” or “masculine.” The term “androgenic” literally is “of man” - “man” representing “mankind” referring to the androgen (testosterone, dihydrotestosterone) that is essential to produce male pattern hair loss. “Genetic” refers to the inherited gene that is imperative for male pattern hair loss to occur. Androgenetic alopecia occurs in both men and women but in different areas of the scalp. Androgenetic alopecia in men is diagnosed under the Norwood-Hamilton Scale of Male Pattern Baldness, while in women it is classified under the Ludwig Classification Scale of Female Pattern Baldness. Androgenetic alopecia is correlated with high levels of DHT (a testosterone derivative, dihydrotestosterone) on the scalp. DHT is thought to penetrate the scalp and cause hair follicle miniaturization, in which follicles become smaller and eventually incapable of supporting a healthy hair growth cycle. By age 35, over 50% of men show signs of male-pattern baldness, and this number increases to 85% by age 50 and approximately 40% of women will experience female pattern hair loss by age 50.
How does laser therapy work for hair loss?
It's fascinating how the red light from lasers can have such positive effects on the scalp and hair follicles. Laser therapy works by stimulating blood flow to the hair follicles, which provides more nutrients to the hair and encourages new growth. The red light from the laser also increases the production of ATP (adenosine triphosphate), which is essential for cell growth and repair. By increasing the amount of ATP in the hair follicles, the laser helps to accelerate the growth cycle of the hair.
The laser also helps to reduce inflammation and oxidative stress in the scalp, which can contribute to hair loss. By reducing inflammation, the laser promotes a healthy environment for hair growth, and by reducing oxidative stress, it helps to prevent damage to the hair follicles.
What is a 650nm laser?
A 650nm laser is a low-level laser therapy (LLLT) device that emits red light at a wavelength of 650nm. This wavelength is within the visible light spectrum and is often referred to as "cold" laser therapy, as it does not produce heat or damage the skin. The red light is absorbed by the hair follicles, which then stimulates cell activity and promotes hair growth.
How effective is a 650nm laser for hair loss?
A 650nm laser has shown effectiveness in promoting hair growth and reducing hair loss, according to several studies. One notable study published in the Journal of Clinical and Aesthetic Dermatology in 2013 demonstrated the efficacy of a 650nm laser in promoting hair growth among both men and women suffering from androgenetic alopecia, which is a common form of hair loss.
Similarly, another study published in the Journal of Cosmetic and Laser Therapy in 2014 supported these findings, showing that a 650nm laser was effective in increasing hair density and thickness specifically in men with male pattern baldness. These studies provide evidence of the effectiveness of 650nm laser therapy as a viable treatment option for hair loss.
Summary: Low-Level Laser Therapy (LLLT) with 650nm light.
This specific wavelength (650nm) falls within the red spectrum of light and has beneficial effects on hair follicles. Here's how 650nm laser light works in the context of hair loss treatment:
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Stimulation of Cellular Activity: Light at a wavelength of 650nm is absorbed by chromophores in cells, particularly in mitochondria, which are the powerhouses of cells responsible for producing energy. This absorption can stimulate cellular activity and metabolism, potentially leading to increased production of adenosine triphosphate (ATP), which provides energy for cellular processes.
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Enhanced Blood Circulation: 650nm light has been shown to promote vasodilation, which can improve blood circulation in the scalp. Better blood flow means more oxygen and nutrients delivered to the hair follicles, supporting their growth and health.
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Reduction of Inflammation: Some studies suggest that 650nm light may have anti-inflammatory effects, which can be beneficial for conditions where inflammation contributes to hair loss.
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Prolongation of Anagen Phase: Anagen is the active growth phase of the hair follicle cycle. LLLT with 650nm light may help prolong this phase, leading to longer periods of active hair growth and potentially thicker, healthier hair.
While low-level laser therapy (LLLT) with 650nm light has shown promise in clinical studies and real-world applications, individual results may vary.